Human Cancer Biology Overexpression of Sirt7 Exhibits Oncogenic Property and Serves as a Prognostic Factor in Colorectal Cancer
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چکیده
Purpose: Sirtuins play an important role in cancer development. Sirt7, as a member of this family, is frequently overexpressed in certain carcinomas, but the oncogenic mechanism is seldom reported. In this study, Sirt7 was characterized for its role in colorectal cancer aggressiveness and underlying molecular
منابع مشابه
Overexpression of sirt7 exhibits oncogenic property and serves as a prognostic factor in colorectal cancer.
PURPOSE Sirtuins play an important role in cancer development. Sirt7, as a member of this family, is frequently overexpressed in certain carcinomas, but the oncogenic mechanism is seldom reported. In this study, Sirt7 was characterized for its role in colorectal cancer aggressiveness and underlying molecular mechanisms. EXPERIMENTAL DESIGN Quantitative PCR, Western blotting, and immunohistoch...
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تاریخ انتشار 2014